SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5701538ccf4e11e417aaaa293e25f618e4a3466809c9738fa49e6157438cb1b' 
  AND token = 'DrZe72lB/1ETR/K/aF6ALSM+dztTUvYVTPI0d0BU3bE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}