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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2d735ecdad1c89950a02ff0b2ed1a1725afe99b25af44f110aaf74b50ec353f' 
  AND token = '6S62QB9DJC6h+XG9jMBjyTTuQufIvTJT2UVhH9etRjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}