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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a91f111f98776355bdbc7819b8bfdbdf0da106e0135b154a708b486bc029511' 
  AND token = 'zmo0QDZz8i31vzCDt7S0gFYcHkdn09LvpjA9bV/DZV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}