SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc528c203b880eacd10adcfa55b9d450b8d67d5319576ca31534ef92bc76b468' 
  AND token = 'fDtOmxSzWVwDRMa+md3LgrGAWyYLuD5P0X5D4jR3jx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}