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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d1d1eb136b498947fb8138c68f1c8e444c665ea2a2957c9e598dc5a192c2dd8' 
  AND token = '1r+AoevY7Xmlc0TjHeWMVC7nG1N5Rng0xeRU4la6we8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}