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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fc2bdd2b921b686b8d3371f542623c96fcd7b2bf54d41a70265b260a933eceb' 
  AND token = 'eQBSxotu7YAV1UpWYTzkaE4a6wzhbJsTa+AhkBzT4L0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}