SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '599d486538725ba6f9bbd8cd9abb6abf109858aa5e4259781c9d10d6c3301bb1' 
  AND token = 'e1kd6FaaO9zlejTLSUeM/G3/1dh+fq5y/NqjmiPMzo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}