SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39ef802ef38608d8feeafd074d7176a4c13ebf08dc4132327f5e23278cf50395' 
  AND token = 'i4EwTs+BzgHMPSfWMdfk8fZcpEPa5+HY9SkGpA4xYFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}