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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef3e8fe7135d4ddd7ce16546d6fffa0e007a4f5c8c5a19e19108d32e915e576d' 
  AND token = 'RsJF4/058NuhrLDcYzOo43NuJ0p+ubH/BZ0YOjIkN0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}