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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17ec9919970a0144c659fe4a778ea0ef10ca8ac7cacb17c0f8fc5beb61873801' 
  AND token = 'bbMHYdNCGixcqrbEnB6hLNpcULucSTwFMOOiAq1z0g4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}