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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01c0a37232bd03265adeb712a7034bc6db45cd3f7073a8a37d79f27e1e4435cf' 
  AND token = 'BtrfapO/FUaG5TdEe30C0S7Rjv0uOaQ+Y6+/G6gs450=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}