SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f5130f69857c934cc65e8aa00dcf904c1183f0b21d70dcb24a946d9aecaf0e2' 
  AND token = 'UVDal1heAW4HBZ4kt2yGpEPVw1H+zMaRy1Co2etS430=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}