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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c4bbc2e11c388277dc063d58320449ac18ac1ec1e8ca07a15c10d9508b306d4' 
  AND token = '2M4ORi6Pxzwed/QaVVfwOi8xQXQ0DD+gNmTtwInCrp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}