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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e55617b5ef35fe2b71d2edb24ccefe8a61941e12d00e4bd133d7dcf62245f549' 
  AND token = 'IGMOLnInxp+DkuBhUqHcuyqs92hMup3yAG1Pf+dbpp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}