SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cecfde7e1d1cff4d28ca785da54e328897e070aeabafd446342c8cb919db6028' 
  AND token = 'Q90FPwl5Ngagyph6N/FEoQWr+GBS+36/yq5KnTc7EFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}