SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e35d3c0f5b9c6b4ed55dac9c229eb63ebf3012dba701684acf758a545d67adaa' 
  AND token = 'eYaXdniNg6JaSOSyf9+1O4XvLZDWk/Mwdd8vbjzAKzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}