SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0cb45d87c3da21daa2bc09e05742489b6bc35a7e23a89bb7d6c3f6242a644e9' 
  AND token = 'b+U18S6w23GhxPDVkFbufgl8lsJycvzlXohME0inQtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}