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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53d1b57a7f6f9f2ffeae81fe62b91186ba52c826a4b6737d36a463b7b5b9a816' 
  AND token = 'zKQMNI6g2cjDpk0wfLW2RHVU81laVJaNRPDqnyelvHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}