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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec1859e1f5607651ec781eedb99a13c78bb73fcff7c55b40e1fc845681f39c60' 
  AND token = '6qucgNWBHqA+iOwZnloVIXB0pRUlCBxfAJIhXX+ahJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}