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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9187b52a276757fe9cb2b54ada29b3d226cc82a7be0352b1d390e8750f882557' 
  AND token = '3seIVtU5M7p5NhnMm8GAzPiMboKn3NZnxK8JBzZGxA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}