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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4163fcac10d9bbf7bfab1c33aeee1ee0756c8c48cba722b7ced3cc9edeacc255' 
  AND token = '+ziT09rz3QTho5SYSzQx/otV0cq0JAAsR9PGy747vs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}