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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68b0b3156feec163e5be97aef90957c819ca6db883e30373ebafe8304c0a87c8' 
  AND token = 'gh1zfA81UXyO5j+IyyBtkgK7X1UQX8XZiqeiN87xbgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}