SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cc3bfdae955c5dfdb061fa6ef8241b7f954e4d0fce0a9fb4033055fea688599' 
  AND token = 'lrOg/e4lxQ6C0k9vcrMOl8CRIOWvn0W1nuiMFLRNgps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}