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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48bb450ce451c141cd304d9a7d4ea5702005992938e9eb66b0601ce535857850' 
  AND token = 'm2EP+jOhcAVmbFGdPkxn8Bmna69GirPZVC07GwXdWQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}