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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f06d5741789f04f8358bc3aa94cdc92c067e218bc2c750ebca5d30d7074e0cd' 
  AND token = 'Rn4gPWjcbTyaI0q6Rsi/eWecF2okRbm0lqb9F1yO2Hg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}