SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a5514ebdcd835a00c266a17e6dd963c2f7e183c15b18cc1eb44e5f4498e902e' 
  AND token = 'AgmIwCZhGG9l1V6KE8KXRkBLLV3Ug3cpT1GXd1WHSZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}