SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7a91714bb2c3652069ed354bc26a9010b7e459b1a2912d2a9813798b2a61f8a' 
  AND token = 'HCH8TaZ6gAhq/Tx+TwCkyc9mclf/rFvg75ZyVU2D4dQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}