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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89559c57b4093721f527cc9c6372e4969dc4c563da02fd2dae8992605c63e8a3' 
  AND token = 'JiBM2q4PJ70zBAdqF8WdrjT5+wVpPnnblV0xWtBFAzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}