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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f32f6c44223fea08b6c88d9ef6abb97c0158b54683643efb85549cab39b728b' 
  AND token = '1MSHMEah24Yi8B1REQ4d3uAHVGpEyf3PKEaNjjIE9Ag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}