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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '533934894a7f3af698162fdd661021e6f5d419feb6c1ecffdb58d1dfc34a653e' 
  AND token = 'TSuiP3TMS9ogCdBKktMS3h2AWq5EAuLKRv6BinbeCZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}