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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd8ad9616ddd9814da8d5740a61539f46231fd0255b3202b505b978eaaa482c0' 
  AND token = 'RWRuDrt8nDEt+R6HxoUIDI3FiJW4ezZ5yArMVf2wPY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}