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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b892d759a824355aac2f8308b3f9434a90196123e046d8292a8c1a6652f0293' 
  AND token = 't0nynxJFjbgX5+M+39KmaokspFI+pegsiQ3o6Bgmid0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}