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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6409f1de6771025e68989ef107d9d7a3295b51b5c4aac057a999f504a49fc7b2' 
  AND token = 'r0/EOG9Iu/WfRzg6hWdbyC3ODMiGhD/vHxT4fC4HSZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}