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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '982c173c48e267e47da721de49ae4150b54e3e354c21a5e4b1a121aa5a9ac875' 
  AND token = 'RnTiMADpvb7mjsnOr0BKvGVWlC1TIUT84oFo3PGqPIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}