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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37af9289c38420f354b4b3853e5dc7b9f3d07a47bc7be46980b649f3625ae6f6' 
  AND token = 'iJSAs7oPDGjDOaK1b5GMzV1DjMScLqshvSMi6cN/PXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}