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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0effd64959fccbc7db0bf2b8ef3c4c8b33a7cf124b6ffffe881898c626a6e08' 
  AND token = 'eYhmtsZEY9KbGSv6wFv7T9YHMyZiY7gtiAAo7PDBu3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}