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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd29825bc0a9c2705283998cf1ce91c2c1297ca52c4edb2cf868130e2301fdc58' 
  AND token = 'PEuopdxb13Kr5GXN7rUUpqqHLMVCfH4Kh5nsfle1gJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}