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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a454f5203e1dbc4a3b9d932e19a356df9de2e4942cbb344ad687e9502ec5496' 
  AND token = 'nxBNELvFGs5IFktSroe+7Z0eRvjpW5SQ+S0TJLdOR1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}