SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8313d3ebf2cb568206d93984363d20b06d01e5f59c72a8cd4aff44e0120d36a6' 
  AND token = 'JqYND5TgYRy1JZ6Cr8TWZRDJ38pxeRvczh4a3zQFJpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}