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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eed39b562c73b6a9ee7575f01113bc649d7f443593a3940256960716f89beedb' 
  AND token = 'JGKHYuraxxx4QiDeAvQep6mjEyOh9CcHC+2rHwJe9Oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}