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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3a5c19eec2fed5ae39c912f57b2074d2cd70951d863b17272641f1161c62864' 
  AND token = 'sgA73c8fO8Clnik69PFFCXYg1QFma0UvbQuDvtHpPn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}