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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83185258ab89dfa600814245d38e4a7e898281cbfb8ccfe5a57d63412f75cafa' 
  AND token = 'sQB2z7+kgtBiOr1goUl4LmkI3OJs8BIRABPs+5Z9aj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}