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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27bbf996c50a03cfa50e8271a1555667fc01a6a0c943050d985b35606bafbb90' 
  AND token = 'pEyijPl+/3GMuHH46z5vGUdhlJuu+QSJdPOr84ptFlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}