SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d3f5e601338ed96c3e756787b25326dc9291b03056c0e08fb5cb57f1caaab53' 
  AND token = 'a9/A49jjoYZIfrrqCbURCv0PDpwUTOMiAOFa2XimbbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}