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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49d314311525c00a04a04eb6f1b89c122b6f8b00193cf58dcb2fac9cab6804af' 
  AND token = '1/Hp98T19Bz9sPXGYBCzoH8VVAfZ0NmjEAdeHHfZVVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}