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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7444580fa21c3dd005eca378ecd9e6d6d6a4ce6356fc732cb74e00ad82850570' 
  AND token = 'J26UtBfZ2/rMg2/ovGJ7E1XrRgxpq5UvPEeQw7PRcpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}