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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ede03bed36d6c2e5098d88e2039d5b7249c6542a230778e7fdfde61f3cd40c6' 
  AND token = 'N+rKP0DY9UpRLKsmFGPMb4Vta7nXDX4puZLEZR0rnpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}