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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38baebf8fb40816e7952fca1ff0136d3230989898085d9f64df6a95327011818' 
  AND token = 'W5IryRfqbDrS7D8TCm5/xWwK2qdSFBLY5nVesLai5qk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}