SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2afbf3b836da9d1e1a128c6288a10cb1bd101fd20092266a3f16c8b908162100' 
  AND token = '6M1SczEbMgHYjejoXlFmGcioNx5wPWGUDo+mF/KFF70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}