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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97478f61ec0b94b9c4c4506b113789ad4f3faa609e3db5a64f11163683a43e3e' 
  AND token = 'PYLH78Qb8MBg7c5QkUglhhjB+0Be0E57Bvj5RFlg0B8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}